First paper: Microtubule doublet in high resolution
- builab
- May 3, 2017
- 1 min read
After 2 years of hard work, we finally published our first paper on the structure of the microtubule doublet at sub-nanometre resolution, the highest to-date for microtubule doublet.
We found that new classes of microtubule-inner proteins, in particular, the filamentous microtubule inner proteins, which bind along the inner ridge of the protofilament pairs.

Link to publication:
https://www.nature.com/articles/ncomms15035
This is such an impressive achievement—congratulations on pushing the boundaries of microtubule research! When I was studying cell biology, I always found it difficult to visualize these tiny structures, so having high-resolution images must be a game-changer for many scientists. On a lighter note, when I need a break from intense reading, I play Slope Game for a quick reset. Sometimes stepping away helps new ideas come to mind!
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That's fascinating research on microtubule doublets! Reading about complex structures like this makes me think of meticulously crafting the perfect pizza in Papa's Pizzeria . Every ingredient, like every protein, needs to be precisely placed for optimal results. Congratulations on publishing your work – a true testament to dedication and precision, much like mastering the art of pizza making.